薄宗义，副教授，兽医学院（比较医学研究院）硕士生导师，扬州大学农业科技发展研究院（教育部农业与农产品安全国际联合实验室）。

科研情况

[1] 国家自然科学基金面上项目，主持。

[2] 国家自然科学基金青年科学基金项目，主持。

[3] 中国博士后基金面上项目，主持。

[4] 江苏省自然科学基金青年科学基金项目，主持。

研究论文

[1] Zongyi Bo, Yurun Miao, Rui Xi, Qiuping Zhong, Chenyi Bao, Huan Chen, Liumei Sun, Yingjuan Qian, Jung YS, Jianjun Dai. PRV UL13 inhibits cGAS-STING-mediated IFN-β production by phosphorylating IRF3. Veterinary Research. 2020 Sep 15;51(1):118.

[2] Zongyi Bo, Yurun Miao, Rui Xi, Xiaoyu Gao, Denian Miao, Hongjun Chen, Yongsam Jung, Yingjuan Qian, Jianjun Dai. Emergence of a novel pathogenic recombinant virus from Bartha vaccine and variant pseudorabies virus in China. Transboundary and Emerging Disease. 2021 May;68(3):1454-1464.

[3] Zongyi Bo, Xiangdong Li. A review of pseudorabies virus variants: genomics, vaccination, transmission, and zoonotic potential. Viruses. 2022, 14:1003.

[4] Zongyi Bo, Xiaojuan Li, Chengcheng Zhang, Mengjiao Guo, Yongzhong Cao, Xiaorong Zhang, Yantao Wu Phosphoproteomic landscape of pseudorabies virus infection reveals multiple potential antiviral targets. Microbiology Spectrum. 2023, 12(1):e03010-23.

[5] Zongyi Bo, Shixu Wang, Keke Xu, Chengcheng Zhang, Mengjiao Guo, Yongzhong Cao, Xiaorong Zhang, Yantao Wu. Isolation and genomic characteristics of the novel variant infectious bursal disease virus in China. Frontiers in Veterinary Science. 2023 Dec 11;10:1314903.

[6] Zongyi Bo, Shuqin Chen, Chengcheng Zhang, Mengjiao Guo, Yongzhong Cao, Xiaorong Zhang, Yantao Wu. Pathogenicity evaluation of GVI-1 lineage infectious bronchitis virus and its long-term effects on reproductive system development in SPF hens. Frontiers in Microbiology. 2022 Oct 28;13:1049287.

[7] Zongyi Bo, Xiaojuan Li, Shixu Wang, Chengcheng Zhang, Mengjiao Guo, Yongzhong Cao, Xiaorong Zhang, Yantao Wu. Suppression of NF-κB signaling by Pseudorabies virus DNA polymerase processivity factor UL42 via recruiting SOCS1 to promote the ubiquitination degradation of p65. Veterinary Microbiology. 2024, 287:109896.

[8] Zongyi Bo, Shixu Wang, Xiaojuan Li, Mengjiao Guo, Chengcheng Zhang, Yongzhong Cao, Xiaorong Zhang, Yantao Wu. Ginkgolic acid inhibits the replication of pseudorabies virus in vitro and in vivo by suppressing the transcription of viral late genes. Research in Veterinary Science. 2023, 164:105033.

[9] Zongyi Bo, Jinjin Zhu, Xiaojuan Li, Chengcheng Zhang, Mengjiao Guo, Yongzhong Cao, Xiaorong Zhang, Yantao Wu. Identification of Na⁺/K⁺-ATPase inhibitor bufalin as a novel pseudorabies virus infection inhibitor in vitro and in vivo. International Journal of Molecular Sciences. 2023, 24(19):14479.

[10] Zongyi Bo, Jinjin Zhu, Mengjiao Guo, Chengcheng Zhang, Yongzhong Cao, Xiaorong Zhang, and Yantao Wu. Gallocatechin gallate inhibits the replication of pseudorabies virus via suppressing the entry and release stages in its replication cycle. Veterinary Sciences. 2023, 10(3):189.

发明专利

[1] 薄宗义，曹永忠，朱进进，郭梦娇，张成成，张小荣，吴艳涛；蟾毒灵在制备抗伪狂犬病毒药物中的用途，授权号：ZL 2023 1 0630069.1。

[2] 薄宗义，朱进进，郭梦娇，张成成，曹永忠，张小荣，吴艳涛；柴胡皂苷D在制备抗猪伪狂犬病毒药物中的用途，CN202310621118.5。