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正高级

Supervisor of Master's Candidates

Date of Birth:1981-05-24

Date of Employment:2019-12-31

School/Department:医学院

Education Level:With Certificate of Graduation for Doctorate Study

Gender:Male

Contact Information:frenksun@126.com

Degree:Doctoral Degree in Medicine

Status:在岗

Alma Mater:南京医科大学

孙海波

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Date of Birth:1981-05-24

Gender:Male

Education Level:With Certificate of Graduation for Doctorate Study

Alma Mater:南京医科大学

Paper Publications

Ultrasound, computed tomography, magnetic resonance, and gamma scintigraphy-based detection and bio-imaging technologies have achieved outstanding breakthroughs in recent years. However, these technologies still encounter several limitations such as insufficient sensitivity, specificity and security that limit their applications in cancer detection and bio-imaging. The semiconductor quantum dots (QDs) are a kind of newly developed fluorescent nanoparticles that have superior fluorescence intensi

Impact Factor:6.2
Journal:Frontiers in Oncology
Abstract:Ultrasound, computed tomography, magnetic resonance, and gamma scintigraphy-based detection and bio-imaging technologies have achieved outstanding breakthroughs in recent years. However, these technologies still encounter several limitations such as insufficient sensitivity, specificity and security that limit their applications in cancer detection and bio-imaging. The semiconductor quantum dots (QDs) are a kind of newly developed fluorescent nanoparticles that have superior fluorescence intensity, strong resistance to photo-bleaching, size-tunable light emission and could produce multiple fluorescent colors under single-source excitation. Furthermore, QDs have optimal surface to link with multiple targets such as antibodies, peptides, and several other small molecules. Thus, QDs might serve as potential, more sensitive and specific methods of detection than conventional methods applied in cancer molecular targeting and bio-imaging. However, many challenges such as cytotoxicity and nonspecific uptake still exist limiting their wider applications. In the present review, we aim to summarize the current applications and challenges of QDs in cancer research mainly focusing on tumor detection, bio-imaging, and provides opinions on how to address these challenges.
Indexed by:Review
Correspondence Author:Zhengyan Liang
Discipline:Medicine
Document Type:SCI
Translation or Not:no
Date of Publication:2021-10-22
Included Journals:SCI