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副高级

Supervisor of Master's Candidates

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School/Department:Institute of Agricultural Science and Technology Development Research (Joint Laboratory for International Cooperation in Agriculture and Agricultural Products Safety of the Ministry of Education)

Education Level:With Certificate of Graduation for Doctorate Study

Business Address:12 Wenhui East Road, Yangzhou, Jiangsu Province,China

Contact Information:E-mail: xstong@yzu.edu.cn

Degree:Doctoral Degree in Agriculture

Status:在岗

Alma Mater:Yangzhou University

Discipline:Clinical Veterinary Medicine

Xishuai Tong

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Education Level:With Certificate of Graduation for Doctorate Study

Alma Mater:Yangzhou University

Paper Publications

siRNA在调控破骨细胞分化和骨吸收中的研究进展

Journal:中国兽医学报
Key Words:破骨细胞;siRNA;Ca2+;AMPK
Abstract:RNAi是指将外源性或内源性的双链RNA导入目的 mRNA序列,特异性转录后基因沉默,又称为转录后基因沉默,广泛应用于基因组学、疾病治疗筛选、药物靶点等众多领域。本文主要介绍破骨细胞(OC)分化和吸收过程中重要的调控分子及信号通路,应用RNAi技术特异性地干扰OC分化和吸收中的相关调控分子及信号通路,找到骨代谢相关疾病的关键靶点,旨在为预防及治疗骨代谢相关疾病提供新的方向和思路。
First Author:仝锡帅,顾建红,刘宗平
Indexed by:Journal paper
Volume:38
Issue:07
Page Number:1451-1456
Translation or Not:no
Date of Publication:2018-07-15