Impact Factor:2.304
DOI number:10.3390/vetsci9010027
Affiliation of Author(s):Yangzhou University
Journal:Veterinary Sciences
Key Words:Avibacterium paragallinarum; infectious coryza; antimicrobial susceptibility; minimum inhibitory concentration
Abstract:Infectious coryza is an acute infectious respiratory disease in chickens that is caused by Avibacterium paragallinarum (A. paragallinarum). Infectious coryza has major economic effects due to decreased egg production in growing birds and slowed growth in broilers. In this study, we isolated and identified 40 strains of A. paragallinarum from chickens that showed typical clinical signs of coryza in part of China from 2019 to 2020. Using a hemagglutination-inhibition test, 11 isolates were identified as serovar A, 10 isolates were identified as serovar B, and 19 isolates were identified as serovar C. Antimicrobial sensitivity tests showed that high minimum inhibitory concentration (MIC) values were encountered for compounds sulfamethoxine sodium and oxytetracycline hydrochloride. Especially, of the 40 A. paragallinarum isolates, 30% had an MIC value of compound sulfamethoxine sodium of 64 μg/mL, 10% of 128 μg/mL, and 15% of 256 μg/mL. For oxytetracycline hydrochloride, 85% of isolates showed MIC values of 64 μg/mL or more. Excitingly, the MIC values of β-lactamase (amoxicillin, ampicillin, and ceftiofur) were low, with 77.5%, 70%, and 92.5% of isolates having an MIC value of ≤1 μg/mL, respectively. Our results may provide a reference for the treatment of infectious coryza.
Co-author:Xiufang Chen,Hao Zhang,Donghui Liu,Yantrao Wu
First Author:Mengjiao Guo
Indexed by:Research Atricle
Correspondence Author:Xiaorong Zhang
Discipline:Agricultural science
First-Level Discipline:Veterinary Medicine
Document Type:J
Volume:9
Issue:1
Page Number:27
ISSN No.:2306-7381
Translation or Not:no
Date of Publication:2022-01-12
Included Journals:SCI