王浩，男，博士，硕士生导师

邮箱：wanghao@yzu.edu.cn

通讯地址：扬州大学文汇路校区生物科学与技术学院109室

研究方向和领域：

细菌与植物互作机制

根癌农杆菌的应用性改造

教育和工作经历：

2020.07年至今，扬州大学生物科学与技术学院，讲师，硕士生导师

2017.10—2018.12，瑞典哥德堡大学，化学与分子生物学系，访问学者

2014.09—2020.06，南京农业大学，植物保护学院，植物病理学，博士

2010.09—2014.06，南京农业大学，植物保护学院，植物保护，学士

科研项目：

1. 根癌农杆菌激活AtuLigM以关闭致病程序的机制研究，国家自然科学基金青年基金，2024.01-2026.12，主持

2. AtuligE增强型根癌农杆菌提高转基因效率的应用研究，江苏高校面上项目，2021.10-2023.09，主持

代表性学术论文：

1. Wang Hao, Zhang Minliang, Wang Erya, Xiao Ruoxuan, Zhang Shuhang, Guo Minliang. Agrobacterium fabrum gene atu1420 regulates the pathogenicity by affecting the degradation of growth- and virulence-associated phenols. Res Microbiol. 2023 174(3):104011.

2. Guo Minliang, Gao Miaomiao, Liu Jinjing, Xu Na, Wang Hao. Bacterioferritin nanocage: Structure, biological function, catalytic mechanism, self-assembly and potential applications. Biotechnol Adv. 2022 Dec;61:108057.

3. 宗仁杰,高苗苗,张梦琪,王浩,徐楠,郭敏亮.根癌农杆菌化学受体MCP1912调节趋化响应功能的鉴定.微生物学报,2022,62(05):1949-1961.

4. Wang Hao, Zhang Mengqi, Xu Yujuan, Zong Renjie, Xu Nan, Guo Minliang. Agrobacterium fabrum atu0526-encoding protein is the only chemoreceptor that regulates chemoattraction toward the broad antibacterial agent formic acid. Biology. 2021 Dec 17;10(12):1345.

5. Ye Jingyang, Gao Miaomiao, Zhou Qin, Wang Hao, Xu Nan, Guo Minliang. The only chemoreceptor encoded by che operon affects the chemotactic Response of agrobacterium to various chemoeffectors. Microorganisms. 2021 Sep 10;9(9):1923.

6. Gao Dawei, Zong Renjie, Huang Zhiwei, Ye Jingyang, Wang Hao, Xu Nan, Guo Minliang. The Divergent Key Residues of Two Agrobacterium fabrum (tumefaciens) CheY Paralogs Play a Key Role in Distinguishing Their Functions. Microorganisms. 2021 24;9(6):1134.

7. Hao Wang, Stefan Schoebel, Florian Schmitz, Hansong Dong, Kristina Hedfalk. Characterization of Aquaporin-driven Hydrogen Peroxide Transport. BBA-Biomembranes. 2020 1862: 183065.

8. Hao Wang, Liyuan Zhang, Yuan Tao, Zuodong Wang, Dan Shen and Hansong Dong. Transmembrane Helices 2 and 3 Determine the Localization of Plasma Membrane Intrinsic Proteins in Eukaryotic Cells. Front Plant Sci. 2020 10;10:1671.

9. Hao Wang, Stefan Schoebel, Florian Schmitz, Hansong Dong, Kristina Hedfalk. Quantitative Analysis of H₂O₂ Transport through Purified Membrane Proteins. Methods X 2020 7: 100816.

10. Shan Tian, Xiaobing Wang, Ping Li, Hao Wang, Hongtao Ji, Junyi Xie, Qinglei Qiu, Dan Shen*, and Hansong Dong. Plant Aquaporin AtPIP1;4 Links Apoplastic H₂O₂ Induction to Disease Immunity Pathways. Plant Physiology 2016 171:1635-1650

11. Liang Li*, Hao Wang*, Jorge Gago, Haiying Cui, Zhengjiang Qian, Naomi Kodama, Hongtao Ji, Shan Tian, Dan Shen, Yanjuan Chen, Fengli Sun, Zhonglan Xia, QingYe, Wei Sun, Jaume Flexas & Hansong Dong. Harpin Hpa1 Interacts with Aquaporin PIP1;4 to Promote the Substrate Transport and Photosynthesis in Arabidopsis. Scientific Reports 2015 5:17207 (*共同一作)

参编图书：

《植物分子免疫学》，科学出版社