Multi-locus sequence typing analysis of Mycoplasma synoviae isolates reveals unique sequence types in China
发布时间：2021-06-17点击次数：
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影响因子：3.03
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DOI码：10.1016/j.vetmic.2021.109101
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所属单位：扬州大学
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发表刊物：Veterinary Microbiology
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关键字：Mycoplasma synoviae
Genotyping
Multi-locus sequence typing
MLST
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摘要：Mycoplasma synoviae is a common pathogen affecting poultry and has important economic significance. Infectious synovitis is the most common clinical effect. Since 2010, the incidence of M. synoviae infection in China has rapidly risen, causing significant economic losses to the chicken industry; however, the cause of the disease outbreak remains unclear. Phylogenetic and evolutionary analyses of field strains will help unravel the mystery. The multi-locus sequence typing (MLST) method is typically utilized to conduct genotyping and traceability analysis of microorganisms. MLST of M. synoviae has previously been established and shown strong discriminatory power. In this study, 54 Chinese M. synoviae strains isolated from 2016 to 2020 were genotyped by MLST based on seven housekeeping genes. This study aimed to investigate the dominant genotypes of M. synoviae in China and reveal the genetic and evolutionary relationships of these isolates. All 54 isolates were found to have new allelic sequences, which may indicate new sequence types. The results of BURST analysis indicated that all 54 strains belonged to group 11, which is an independent phylogenetic branch, and were separated from any other reference strains (189 isolates) in the PubMLST database. In conclusion, the results of this study suggest that the M. synoviae strains circulating in China are relatively independent in terms of transmission and evolutionary relationships.
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合写作者：陈杨,谢迪,郭梦娇,马爽,陈梦瑶,楚电峰
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第一作者：张小荣
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论文类型：Research Atricle
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通讯作者：吴艳涛
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学科门类：农学
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一级学科：兽医学
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文献类型：J
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卷号：259
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页面范围：109101
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ISSN号：0378-1135
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是否译文：否
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发表时间：2021-06-17
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收录刊物：SCI
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张小荣
个人信息
- 正高级
博士生导师
硕士生导师 - 教师拼音名称：Zhang Xiaorong
- 出生日期：1978-09-30
- 电子邮箱：
- 入职时间：2003-07-01
- 所在单位：兽医学院
- 学历：博士研究生毕业
- 办公地点：文汇路校区农牧南楼S203
- 性别：男
- 联系方式：E.mail:zxr@yzu.edu.cn
- 学位：博士
- 职称：正高级
- 在职信息：在岗
- 毕业院校：扬州大学
- 学科：预防兽医学
曾获荣誉：
- 2021-12-31扬州大学“十三五”科技工作先进个人
- 2021-10-222020-2021学年“最受学生欢迎的班主任”
- 2017-06-302016年江苏省普通高等学校本专科毕业设计（论文）三等奖指导教师
- 2016-01-182014-2015学年“最受学生欢迎的班主任”
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